3,3-Dimethyl-1,2,3,4-tetrahydroisoquinoline → HCID 24810078, 화합물

HRID 1015090노트

반응식

HRID 1015090 반응식
[Cl:1][C:2]1[CH:3]=[N:4][C:5]2[N:6]([N:8]=[C:9]([C:11]([OH:13])=O)[CH:10]=2)[CH:7]=1.[CH3:14][C:15]1([CH3:25])[CH2:24][C:23]2[C:18](=[CH:19][CH:20]=[CH:21][CH:22]=2)[CH2:17][NH:16]1>>[Cl:1][C:2]1[CH:3]=[N:4][C:5]2[N:6]([N:8]=[C:9]([C:11]([N:16]3[C:15]([CH3:25])([CH3:14])[CH2:24][C:23]4[C:18](=[CH:19][CH:20]=[CH:21][CH:22]=4)[CH2:17]3)=[O:13])[CH:10]=2)[CH:7]=1

참가 물질

3

반응물 2

HCID 109865563,3-Dimethyl-1,2,3,4-tetrahydroisoquinolineHCID 336956786-Chloropyrazolo[1,5-A]pyrimidine-2-carboxylic acid

생성물 1

HCID 24810078HCID 24810078, 화합물

실험 절차

In close analogy to the procedure described in Example 1, 6-chloro-pyrazolo[1,5-a]pyrimidine-2-carboxylic acid is reacted with 3,3-dimethyl-1,2,3,4-tetrahydro-isoquinoline to provide the title compound in moderate yield.

출처 및 근거

ORD 기록
ord-98563bfbbe554dd7bcf0491264ecabbd
출처 데이터셋
uspto-grants-2011_07
특허 번호
US07985753B2

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