HCID 583452, 화합물 → HCID 24810630, 화합물

HRID 1015146노트

반응식

HRID 1015146 반응식
[Cl:1][C:2]1[CH:3]=[N:4][C:5]2[N:6]([N:8]=[C:9]([C:11]([OH:13])=O)[CH:10]=2)[CH:7]=1.[CH:14]([CH:17]1[C:26]2[C:21](=[CH:22][CH:23]=[CH:24][CH:25]=2)[CH2:20][CH2:19][NH:18]1)([CH3:16])[CH3:15]>>[Cl:1][C:2]1[CH:3]=[N:4][C:5]2[N:6]([N:8]=[C:9]([C:11]([N:18]3[CH2:19][CH2:20][C:21]4[C:26](=[CH:25][CH:24]=[CH:23][CH:22]=4)[CH:17]3[CH:14]([CH3:16])[CH3:15])=[O:13])[CH:10]=2)[CH:7]=1

참가 물질

3

반응물 2

HCID 583452HCID 583452, 화합물HCID 336956786-Chloropyrazolo[1,5-A]pyrimidine-2-carboxylic acid

생성물 1

HCID 24810630HCID 24810630, 화합물

실험 절차

In close analogy to the procedure described in Example 1, 6-chloro-pyrazolo[1,5-a]pyrimidine-2-carboxylic acid is reacted with 1-Isopropyl-1,2,3,4-tetrahydro-isoquinoline to provide the title compound in moderate yield.

출처 및 근거

ORD 기록
ord-5d714f858ade475582af5456c7c20c10
출처 데이터셋
uspto-grants-2011_07
특허 번호
US07985753B2

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