Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Formic Acid → 4-(4-Oxocyclohexyloxy)-3-methoxy-2-methylpyridine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Formic Acid | HCID 284 | — |
| 반응물 | 4-(3,3-Dimethyl-1,5-dioxaspiro[5.5]undecan-9-yloxy)-3-methoxy-2-methylpyridine | HCID 19693934 | — |
| 용매 | Acetone | HCID 180 | — |
| 생성물 | 4-(4-Oxocyclohexyloxy)-3-methoxy-2-methylpyridine | HCID 19694031 | — |
반응 단계
1 g of 4-(3,3-dimethyl-1,5-dioxaspiro[5.5]undecan-9-yloxy)-3-methoxy-2-methylpyridine is stirred with 20 ml of formic acid and 5 ml of acetone for 5 hours. The residue which remains after concentrating is purified by chromatography on silica gel using ethyl acetate. 0.3 g=41%; m.p.: 56° to 57° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05723450 |
| 출처 데이터셋 | uspto-grants-1998_03 |
| ORD ID | ord-91ac38e1cd644fcdbb0f2037b7004087 |
| 출처 메모 | uspto-grants-1998_03 |