HCID 602709, 화합물 → HCID 22039032, 화합물
반응식
[CH2:1]([O:3][C:4]1[CH:5]=[C:6]([CH2:12][OH:13])[CH:7]=[C:8]([CH2:10][OH:11])[CH:9]=1)[CH3:2]>C(Cl)Cl.O=[Mn]=O>[CH2:1]([O:3][C:4]1[CH:5]=[C:6]([CH:7]=[C:8]([CH2:10][OH:11])[CH:9]=1)[CH:12]=[O:13])[CH3:2]참가 물질
4
실험 절차
MnO2 (8.37 g, 96.3 mmol) was added to a solution of (3-ethoxy-5-hydroxymethyl-phenyl)-methanol (17.55 g, 96.3 mmol) in CH2Cl2 (175 ml) and the mixture was stirred for 64 h. at room temperature. Thereafter, further MnO2 (8.37 g, 96.3 mmol) was added and the mixture was stirred for 6 h. The mixture was filtered over Celite and the filtrate was concentrated. The product was purified by chromatography. There were obtained 8.32 g (48%) of 3-ethoxy-5-hydroxymethyl-benzaldehyde as a colorless oil.
후처리
- stirringthe mixture was stirred for 6 h
- filtrationThe mixture was filtered over Celite
- concentrationthe filtrate was concentrated
- customThe product was purified by chromatography
출처 및 근거
- ORD 기록
- ord-c50574a75bc5446180dda64a4ff316fd
- 출처 데이터셋
- uspto-grants-2002_11
- 특허 번호
- US06476264B2
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