Acetaldehyde → 2-chloroethanal O-[2-(morpholin-4-yl)ethyl]oxime

참여 물질

반응 단계

A mixture of acetaldehyde (0.1 mL of a 50 wt % soln. in water), O-[2-((morpholin-4-yl))ethyl]hydroxylamine dihydrochloride (0.14 g), NaOH (2N, 0.64 mL) and water (5 mL) was stirred at room temperature overnight. The solution was made basic with NaOH (1N) and extracted with dichloromethane. The organic layer was dried (Na2SO4), and concentrated in vacuo to afford 2-chloroethanal O-[2-((morpholin-4-yl))ethyl]oxime (0.13 g, ˜100%), which was used as such.

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