Ethyl bromoacetate → Ethyl alpha-(1-hydroxy-6-methoxy-2-methyl-1-indanyl)propionate
반응식
[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:9](=[CH:10][CH:11]=1)[CH2:8][C:7]([CH3:12])=[C:6]2[CH:13]([CH3:17])[C:14]([OH:16])=[O:15].Br[CH:19](C)[C:20](OCC)=O.BrCC(OCC)=[O:29]>>[OH:29][C:6]1([CH:13]([CH3:17])[C:14]([O:16][CH2:19][CH3:20])=[O:15])[C:5]2[C:9](=[CH:10][CH:11]=[C:3]([O:2][CH3:1])[CH:4]=2)[CH2:8][CH:7]1[CH3:12]참가 물질
4
실험 절차
The procedure of Example 35, part (A) is followed using ethyl α-bromopropionate in equivalent quantities in place of ethyl bromoacetate used therein. There is obtained ethyl α-(1-hydroxy-6-methoxy-2-methyl-1-indanyl)propionate, which is dehydrated to ethyl α-(5-methoxy-2-methyl-3-indenyl)propionate in the same manner.
출처 및 근거
- ORD 기록
- ord-fd21a34cf0564214a3a1ac9abe00d56d
- 출처 데이터셋
- uspto-grants-2002_11
- 특허 번호
- US06479493B1
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