4-Piperidone → 1-(1H-Benzimidazol-2-ylmethyl)-4-piperidinone

반응식

[NH:1]1[CH2:6][CH2:5][C:4](=[O:7])[CH2:3][CH2:2]1.Cl[CH2:9][C:10]1[NH:11][C:12]2[CH:18]=[CH:17][CH:16]=[CH:15][C:13]=2[N:14]=1>>[N:11]1[C:12]2[CH:18]=[CH:17][CH:16]=[CH:15][C:13]=2[NH:14][C:10]=1[CH2:9][N:1]1[CH2:6][CH2:5][C:4](=[O:7])[CH2:3][CH2:2]1

참가 물질

반응물 2

HCID 337214-Piperidone

HCID 785712-Chloromethylbenzimidazole

생성물 1

HCID 117910041-(1H-Benzimidazol-2-ylmethyl)-4-piperidinone

실험 절차

1-(2-Benzimidazolyl)methyl-4-piperidone is prepared from 4-piperidone and 2-(chloromethyl)benzimidazole essentially as described above in Example 38, Scheme C, step a.

출처 및 근거

ORD 기록: ord-6efc46fd87644796b3ea55ba1d8959c6
출처 데이터셋: uspto-grants-2002_11
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06479487B1

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