3-Methoxybenzaldehyde → 6-(3-methoxyphenyl)-7H-[1,3]dioxolo[4,5-g]quinazolin-8-one

HRID 1017529

반응식

HRID 1017529 반응식
COC1C=CC=CC=1C1NC(=O)C2C(=CC=CC=2)N=1.[NH2:20][C:21]1[CH:29]=[C:28]2[O:30][CH2:31][O:32][C:27]2=[CH:26][C:22]=1[C:23]([NH2:25])=[O:24].[CH3:33][O:34][C:35]1[CH:36]=[C:37]([CH:40]=[CH:41][CH:42]=1)[CH:38]=O>>[CH3:33][O:34][C:35]1[CH:36]=[C:37]([C:38]2[NH:25][C:23](=[O:24])[C:22]3[C:21](=[CH:29][C:28]4[O:30][CH2:31][O:32][C:27]=4[CH:26]=3)[N:20]=2)[CH:40]=[CH:41][CH:42]=1

참가 물질

4

반응물 3

HCID 115693-MethoxybenzaldehydeHCID 107260536-Aminobenzo[D][1,3]dioxole-5-carboxamideHCID 135436005HCID 135436005, 화합물

생성물 1

HCID 1355111016-(3-methoxyphenyl)-7H-[1,3]dioxolo[4,5-g]quinazolin-8-one수율 8.8%

실험 절차

According to the preparation of 42, 16 (1.0 g, 5.5 mmol) and 3-methoxybenzaldehyde (34) (0.7 g, 5.5 mmol) were used to afford 54 (0.1 g, 8.8%) as pale yellow needles.

출처 및 근거

ORD 기록
ord-6a306b9813ee4e3eb0d56078bb324aed
출처 데이터셋
uspto-grants-2002_11
특허 번호
US06479499B1

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