Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Fluorobenzoyl chloride → 4-Fluoro-N-[3-(4-isopropylphenyl)-1',4,6,7-tetramethylspiro[benzofuran-2(3H),4'-piperidine]-5-yl]benzamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Fluorobenzoyl chloride | HCID 67879 | — |
| 반응물 | Diisopropylether methanol | HCID 21882575 | — |
| 반응물 | 3-(4-Isopropylphenyl)-1',4,6,7-tetramethylspiro[benzofuran-2(3H),4'-piperidine]-5-amine | HCID 21961302 | — |
| 생성물 | 4-Fluoro-N-[3-(4-isopropylphenyl)-1',4,6,7-tetramethylspiro[benzofuran-2(3H),4'-piperidine]-5-yl]benzamide | HCID 10185404 | 38% |
반응 단계
By using 3-(4-isopropylphenyl)-1′,4,6,7-tetramethylspiro[benzofuran-2(3H),4′-piperidine]-5-amine and 4-fluorobenzoyl chloride, the title compound was synthesized according to Example 1b. Yield: 38%. Melting point: 271-272° C. (Methanol-isopropyl ether)
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06479536B1 |
| 출처 데이터셋 | uspto-grants-2002_11 |
| ORD ID | ord-33988106ccf94bc780a4bf9a2e7df83f |
| 출처 메모 | uspto-grants-2002_11 |