Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Citronellol → 4-Oxo-decanoic Acid 3,7-dimethyl-oct-6-enyl Ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Citronellol | HCID 8842 | — |
| 반응물 | 4-Oxo capric acid | HCID 538647 | — |
| 촉매 | p-Toluenesulfonic acid | HCID 6101 | — |
| 용매 | Diethyl Ether | HCID 3283 | — |
| 용매 | Cyclohexane | HCID 8078 | — |
| 생성물 | 4-Oxo-decanoic Acid 3,7-dimethyl-oct-6-enyl Ester | HCID 53830542 | 91% |
반응 단계
A solution of 20.0 g 4-oxo-1-decanoic acid (Synthesis, 1987, 408), 16.8 g citronellol extra and 0.5 g p-toluene-sulfonic acid in 150 ml of cyclohexane was refluxed in a flask equipped with a Dean-Stark trap for 3 hours. Then the reaction mixture was cooled, diluted with ether, washed with saturated NaHCO3 and water. The organic phase was dried, filtered and evaporated to dryness. The resulting oil was purified by chromatography to yield 31.7 g of a yellow oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06479682B1 |
| 출처 데이터셋 | uspto-grants-2002_11 |
| ORD ID | ord-11630feaa8de4c1b838b6cbecb81d087 |
| 출처 메모 | uspto-grants-2002_11 |