Aminopyrazine → 3-Cycloheptyl-2-(1-oxo-1,3-dihydro-isoindol-2-yl)-N-thiazol-2-yl-propionamide

반응식

F[P-](F)(F)(F)(F)F.N1(O[P+](N(C)C)(N(C)C)N(C)C)C2C=CC=C[C:11]=2N=N1.C1(C[C@H](N2CC3C(=CC=CC=3S(C)(=O)=O)C2=O)C(O)=O)CCCCC1.C1(C[C@H](N2CC3C(=C(S(C)(=O)=O)C=CC=3)C2=O)C(O)=O)CCCCC1.NC1C=NC=CN=1.[CH:85]1([CH2:91][C@H:92]([N:101]2[CH2:109][C:108]3[C:103](=[CH:104][CH:105]=[CH:106][CH:107]=3)[C:102]2=[O:110])[C:93]([NH:95][C:96]2[S:97][CH:98]=[CH:99][N:100]=2)=[O:94])[CH2:90][CH2:89][CH2:88][CH2:87][CH2:86]1>C(OCC)(=O)C.C(Cl)Cl>[CH:85]1([CH2:91][CH:92]([N:101]2[CH2:109][C:108]3[C:103](=[CH:104][CH:105]=[CH:106][CH:107]=3)[C:102]2=[O:110])[C:93]([NH:95][C:96]2[S:97][CH:98]=[CH:99][N:100]=2)=[O:94])[CH2:86][CH2:87][CH2:88][CH2:89][CH2:90][CH2:11]1