Benzotriazol-1-yloxy-tris(dimethylamino)phosphonium hexafluorophosphate → (S)-3-Cyclohexyl-N-(2-methyl-pyrimidin-4-yl)-2-(1-oxo-1,3-dihydro-isoindol-2-yl)-propionamide

반응식

F[P-](F)(F)(F)(F)F.N1(O[P+](N(C)C)(N(C)C)N(C)C)C2C=CC=CC=2N=N1.C1(C[C@H](N2CC3C(=CC=CC=3)C2=O)C(O)=O)CCCCC1.[NH2:49][C:50]1[CH:55]=[CH:54][CH:53]=[CH:52][N+:51]=1[O-].[CH:57]1([CH2:63][C@@H:64]([N:73]2[CH2:81][C:80]3[C:75](=[CH:76][CH:77]=[CH:78][CH:79]=3)[C:74]2=[O:82])[C:65]([NH:67]C2SC=CN=2)=[O:66])[CH2:62][CH2:61][CH2:60][CH2:59][CH2:58]1>>[CH:57]1([CH2:63][C@H:64]([N:73]2[CH2:81][C:80]3[C:75](=[CH:76][CH:77]=[CH:78][CH:79]=3)[C:74]2=[O:82])[C:65]([NH:67][C:52]2[CH:53]=[CH:54][N:49]=[C:50]([CH3:55])[N:51]=2)=[O:66])[CH2:62][CH2:61][CH2:60][CH2:59][CH2:58]1