Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1019314생성일: 2026년 10월 26일
Stearamidopropyl Dimethylamine → N,N-dimethyl-N-geranyloxycarbonylmethyl-N-(3-(octadecanoylamino)propyl)ammonium chloride
https://huagongshe.com/reaction/1019314
참여 물질
| 역할 | 이름 | HCID | 투입량 |
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| 반응물 | Stearamidopropyl Dimethylamine | HCID 62109 | — |
| 반응물 | Chloroacetate | HCID 518964 | — |
| 반응물 | (E)-3,7-dimethylocta-2,6-dienyl 2-chloroacetate | HCID 5890636 | — |
| 용매 | Chloroform | HCID 6212 | — |
| 생성물 | N,N-dimethyl-N-geranyloxycarbonylmethyl-N-(3-(octadecanoylamino)propyl)ammonium chloride | HCID 11433380 | 81.9% |
반응 단계
A 36.86 g (0.100 mol) portion of N-octadecanoyl-N′,N′-dimethyl-1,3-diaminopropane and 100 ml of chloroform were put into a flask, and 23.30 g (0.101 mol) of geranyl chloroacetate was added thereto at 25° C. spending 5 minutes. The reaction mixture was stirred at 25° C. for 36 hours and then, after confirming by 1H-NMR that chloroacetate was mostly disappeared, the solvent was evaporated under a reduced pressure. The thus obtained viscous oil was dissolved in 200 ml of acetone and cooled to 5 to 10° C. to effect precipitation of a white precipitate. The supernatant solvent was discarded, and the precipitated was collected and dried under a reduced pressure to obtain the title compound (to be referred to as betaine ester (1) hereinafter) as a slightly brownish white solid. Yield 49.1 g (0.0819 mol; yield 81.9%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| 특허 번호 | US06486333B1 |
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| 출처 데이터셋 | uspto-grants-2002_11 |
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| ORD ID | ord-a583b89735d44ed8918454e41366424d |
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| 출처 메모 | uspto-grants-2002_11 |
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