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HRID 1019314생성일: 2026년 10월 26일

Stearamidopropyl Dimethylamine → N,N-dimethyl-N-geranyloxycarbonylmethyl-N-(3-(octadecanoylamino)propyl)ammonium chloride

https://huagongshe.com/reaction/1019314

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참여 물질

역할이름HCID투입량
반응물Stearamidopropyl DimethylamineHCID 62109—
반응물ChloroacetateHCID 518964—
반응물(E)-3,7-dimethylocta-2,6-dienyl 2-chloroacetateHCID 5890636—
용매ChloroformHCID 6212—
생성물N,N-dimethyl-N-geranyloxycarbonylmethyl-N-(3-(octadecanoylamino)propyl)ammonium chlorideHCID 1143338081.9%

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온도25 °C

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A 36.86 g (0.100 mol) portion of N-octadecanoyl-N′,N′-dimethyl-1,3-diaminopropane and 100 ml of chloroform were put into a flask, and 23.30 g (0.101 mol) of geranyl chloroacetate was added thereto at 25° C. spending 5 minutes. The reaction mixture was stirred at 25° C. for 36 hours and then, after confirming by 1H-NMR that chloroacetate was mostly disappeared, the solvent was evaporated under a reduced pressure. The thus obtained viscous oil was dissolved in 200 ml of acetone and cooled to 5 to 10° C. to effect precipitation of a white precipitate. The supernatant solvent was discarded, and the precipitated was collected and dried under a reduced pressure to obtain the title compound (to be referred to as betaine ester (1) hereinafter) as a slightly brownish white solid. Yield 49.1 g (0.0819 mol; yield 81.9%).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US06486333B1
출처 데이터셋uspto-grants-2002_11
ORD IDord-a583b89735d44ed8918454e41366424d
출처 메모uspto-grants-2002_11