Phenyl 5-cyanopyrazin-2-ylcarbamate → 4-(4-{(S)-1-[tert-Butoxycarbonyl-(2-{2-chloro-4-[3-(5-cyano-pyrazin-2-yl)-ureido]-5-methoxy-phenyl}-ethyl)-amino]-ethyl}-phenyl)-piperazine-1-carboxylic acid tert-butyl ester

반응식

[C:1]([O:5][C:6]([N:8]1[CH2:13][CH2:12][N:11]([C:14]2[CH:19]=[CH:18][C:17]([C@@H:20]([N:22]([CH2:30][CH2:31][C:32]3[CH:37]=[C:36]([O:38][CH3:39])[C:35]([NH2:40])=[CH:34][C:33]=3[Cl:41])[C:23]([O:25][C:26]([CH3:29])([CH3:28])[CH3:27])=[O:24])[CH3:21])=[CH:16][CH:15]=2)[CH2:10][CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2].[C:42]([C:44]1[N:45]=[CH:46][C:47]([NH:50][C:51](=O)[O:52]C2C=CC=CC=2)=[N:48][CH:49]=1)#[N:43]>CN(C=O)C.O>[C:1]([O:5][C:6]([N:8]1[CH2:13][CH2:12][N:11]([C:14]2[CH:19]=[CH:18][C:17]([C@@H:20]([N:22]([C:23]([O:25][C:26]([CH3:28])([CH3:29])[CH3:27])=[O:24])[CH2:30][CH2:31][C:32]3[CH:37]=[C:36]([O:38][CH3:39])[C:35]([NH:40][C:51]([NH:50][C:47]4[CH:46]=[N:45][C:44]([C:42]#[N:43])=[CH:49][N:48]=4)=[O:52])=[CH:34][C:33]=3[Cl:41])[CH3:21])=[CH:16][CH:15]=2)[CH2:10][CH2:9]1)=[O:7])([CH3:2])([CH3:3])[CH3:4]