2-Methanesulfonyl-5-phenylethynyl-pyrimidine → HCID 178496605, 화합물

HRID 1020166노트

반응식

HRID 1020166 반응식
CS([C:5]1[N:10]=[CH:9][C:8]([C:11]#[C:12][C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)=[CH:7][N:6]=1)(=O)=O.Cl.[CH3:20][O:21][C@H:22]1[CH2:27][CH2:26][C@H:25]([NH2:28])[CH2:24][CH2:23]1>>[CH3:20][O:21][C@H:22]1[CH2:27][CH2:26][C@H:25]([NH:28][C:5]2[N:10]=[CH:9][C:8]([C:11]#[C:12][C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=3)=[CH:7][N:6]=2)[CH2:24][CH2:23]1

참가 물질

3

반응물 2

HCID 575167582-Methanesulfonyl-5-phenylethynyl-pyrimidineHCID 178496611HCID 178496611, 화합물

생성물 1

HCID 178496605HCID 178496605, 화합물

실험 절차

The title compound, MS: m/e=308.5 (M+H+), can be prepared in accordance with the general method of example 1, step 3 from 2-methanesulfonyl-5-phenylethynyl-pyrimidine (example 1, step 2) and trans-4-methoxycyclohexanamine hydrochloride.

출처 및 근거

ORD 기록
ord-272a2071c965436c9664195cb7c1c085
출처 데이터셋
uspto-grants-2014_05
특허 번호
US08716316B2

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