4-(4-(2-Methoxyethoxy)phenyl)cyclohexylamine → 3-Chloro-4-[4-(4-(2-methoxyethoxy)phenyl)cyclohexylamino)-2-ethylpyridine
반응식
[Cl:1][C:2]1[C:3]([CH2:9][CH3:10])=[N:4][CH:5]=[CH:6][C:7]=1Cl.[CH3:11][O:12][CH2:13][CH2:14][O:15][C:16]1[CH:21]=[CH:20][C:19]([CH:22]2[CH2:27][CH2:26][CH:25]([NH2:28])[CH2:24][CH2:23]2)=[CH:18][CH:17]=1>>[Cl:1][C:2]1[C:3]([CH2:9][CH3:10])=[N:4][CH:5]=[CH:6][C:7]=1[NH:28][CH:25]1[CH2:24][CH2:23][CH:22]([C:19]2[CH:18]=[CH:17][C:16]([O:15][CH2:14][CH2:13][O:12][CH3:11])=[CH:21][CH:20]=2)[CH2:27][CH2:26]1참가 물질
3
실험 절차
Preparation took place analogously to Example 59 from 3,4-dichloro-2-ethylpyridine and 4-(4-(2-methoxyethoxy)phenyl)cyclohexylamine. Yield: 11% (cis/trans mixture)
후처리
- customPreparation
출처 및 근거
- ORD 기록
- ord-604b730a698f47929475fa327db8b570
- 출처 데이터셋
- uspto-grants-1998_03