3-Nitrodibenzofuran → 3-Dibenzofuranamine
반응식
[N+:1]([C:4]1[CH:5]=[CH:6][C:7]2[C:11]3[CH:12]=[CH:13][CH:14]=[CH:15][C:10]=3[O:9][C:8]=2[CH:16]=1)([O-])=O>C(OCC)(=O)C>[NH2:1][C:4]1[CH:5]=[CH:6][C:7]2[C:11]3[CH:12]=[CH:13][CH:14]=[CH:15][C:10]=3[O:9][C:8]=2[CH:16]=1참가 물질
3
실험 절차
3-nitrodibenzofuran (6.2 g, 29.08 mmol) was dissolved in 360 mL ethyl acetate and was degassed 5 minutes by passing nitrogen gas through the solution. 500 mg of Pd/C was added to the solution and the content was hydrogenated at 60 psi pressure. Reaction was let go until pressure in hydrogenation apparatus stabilizes at 60 psi for 15 minutes. Reaction content was then filtered through a small celite pad and off white color product was obtained. (5.3 g, 28.9 mmol)
후처리
- customwas degassed 5 minutes
- addition500 mg of Pd/C was added to the solution
- customReaction
- customReaction content
- filtrationwas then filtered through a small celite pad and off white color product
- customwas obtained
출처 및 근거
- ORD 기록
- ord-4690163f545442f396f0c36b703b0d76
- 출처 데이터셋
- uspto-grants-2014_05
- 특허 번호
- US08722205B2
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