Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hippuric Acid → N-[2-({[(6S,7R)-7-(4-chloro-3-fluorophenyl)-1,4-oxazepan-6-yl]methyl}amino)-2-oxoethyl]benzamide monohydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hippuric Acid | HCID 464 | — |
| 반응물 | tert-butyl (6R,7R)-6-(aminomethyl)-7-(4-chloro-3-fluorophenyl)-1,4-oxazepane-4-carboxylate | HCID 66975002 | — |
| 생성물 | N-[2-({[(6S,7R)-7-(4-chloro-3-fluorophenyl)-1,4-oxazepan-6-yl]methyl}amino)-2-oxoethyl]benzamide monohydrochloride | HCID 66975533 | — |
반응 단계
Using tert-butyl (6R,7R)-6-(aminomethyl)-7-(4-chloro-3-fluorophenyl)-1,4-oxazepane-4-carboxylate and N-(phenylcarbonyl)glycine, and by a method similar to that of Example 39, the title compound was obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08722662B2 |
| 출처 데이터셋 | uspto-grants-2014_05 |
| ORD ID | ord-8c1cfdb656154ac99f0774ebcf950edb |
| 출처 메모 | uspto-grants-2014_05 |