2-(2-oxopyrrolidin-1-yl)benzoic Acid → HCID 66976096, 화합물
반응식
[NH2:1][CH2:2][C@H:3]1[C@H:9]([C:10]2[CH:15]=[CH:14][C:13]([Cl:16])=[C:12]([F:17])[CH:11]=2)[O:8][CH2:7][CH2:6][N:5](C(OC(C)(C)C)=O)[CH2:4]1.[O:25]=[C:26]1[CH2:30][CH2:29][CH2:28][N:27]1[C:31]1[CH:39]=[CH:38][CH:37]=[CH:36][C:32]=1[C:33](O)=[O:34]>>[ClH:16].[Cl:16][C:13]1[CH:14]=[CH:15][C:10]([C@@H:9]2[O:8][CH2:7][CH2:6][NH:5][CH2:4][C@H:3]2[CH2:2][NH:1][C:33](=[O:34])[C:32]2[CH:36]=[CH:37][CH:38]=[CH:39][C:31]=2[N:27]2[CH2:28][CH2:29][CH2:30][C:26]2=[O:25])=[CH:11][C:12]=1[F:17]참가 물질
3
실험 절차
Using tert-butyl (6R,7R)-6-(aminomethyl)-7-(4-chloro-3-fluorophenyl)-1,4-oxazepane-4-carboxylate and 2-(2-oxopyrrolidin-1-yl)benzoic acid, and by a method similar to that of Example 39, the title compound was obtained.
출처 및 근거
- ORD 기록
- ord-97414353ca77479f81a7cdb45e66e289
- 출처 데이터셋
- uspto-grants-2014_05
- 특허 번호