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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1022772생성일: 2026년 10월 26일

N-acetylanthranilic acid → 3-{[(6S,7R)-7-(4-chloro-3-fluorophenyl)-1,4-oxazepan-6-yl]methyl}-2-methylquinazolin-4(3H)-one monohydrochloride

https://huagongshe.com/reaction/1022772

반응식

참여 물질

역할이름HCID투입량
반응물N-acetylanthranilic acidHCID 6971—
반응물tert-butyl (6R,7R)-6-(aminomethyl)-7-(4-chloro-3-fluorophenyl)-1,4-oxazepane-4-carboxylateHCID 66975002—
생성물3-{[(6S,7R)-7-(4-chloro-3-fluorophenyl)-1,4-oxazepan-6-yl]methyl}-2-methylquinazolin-4(3H)-one monohydrochlorideHCID 66976700—

반응 단계

Using tert-butyl (6R,7R)-6-(aminomethyl)-7-(4-chloro-3-fluorophenyl)-1,4-oxazepane-4-carboxylate and 2-(acetylamino)benzoic acid, and by a method similar to that of Example 39, the title compound was obtained.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08722662B2
출처 데이터셋uspto-grants-2014_05
ORD IDord-752753948b8e49edab6ff8b64c1b4bbd
출처 메모uspto-grants-2014_05