HCID 86673589, 화합물 → HCID 67235532, 화합물
반응식
C[C@@H](NC(=O)[O-])C(NC1C=CC(OC2C=C(OC)C=CC=2C)=CC=1)=O.CC([N:30]([C@H:34]([CH3:54])[C:35]([NH:37][C:38]1[CH:39]=[N:40][C:41]([O:44][C:45]2[CH:50]=[C:49]([O:51][CH3:52])[CH:48]=[CH:47][C:46]=2[CH3:53])=[CH:42][CH:43]=1)=[O:36])C(=O)[O-])(C)C>>[CH3:53][C:46]1[CH:47]=[CH:48][C:49]([O:51][CH3:52])=[CH:50][C:45]=1[O:44][C:41]1[N:40]=[CH:39][C:38]([NH:37][C:35](=[O:36])[C@@H:34]([CH3:54])[NH2:30])=[CH:43][CH:42]=1참가 물질
3
실험 절차
The title compound was made in a similar fashion to the preparation of Intermediate 16 replacing {(1R)-1-methyl-2-[(4-{[2-methyl-5-(methyloxy)phenyl]oxy}phenyl)amino]-2-oxoethyl}carbamate with 1,1-dimethylethyl{(1R)-1-methyl-2-[(6-{[2-methyl-5-(methyloxy)phenyl]oxy}-3-pyridinyl)amino]-2-oxoethyl}carbamate (Intermediate 55, 150 mg) to afford the title compound (120 mg).
출처 및 근거
- ORD 기록
- ord-bf3ea6d42d444968a1b862e10ad5a329
- 출처 데이터셋
- uspto-grants-2014_05