Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Boron tribromide → 2-(4-Methoxyphenoxy)-5-propylphenol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Boron tribromide | HCID 25134 | — |
| 반응물 | 2-Methoxy-1-(4-methoxyphenoxy)-4-propylbenzene | HCID 24786192 | — |
| 생성물 | 2-(4-Methoxyphenoxy)-5-propylphenol | HCID 59191206 | 32% |
반응 단계
According to the procedure of example 5(b) except substituting 2-fluoro-6-(2-methoxy-4-propylphenoxy)pyridine for 2-methoxy-1-(4-methoxyphenoxy)-4-propylbenzene (0.18 mmol; 50 mg) and adding 4 equivalents (0.735 mmol; 735 μl) of boron tribromide, the title compound was prepared in 32% yield (0.06 mmol; 15 mg) after purification by preparative TLC on silica gel (ethyl acetate/cyclohexane—20/80).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08722746B2 |
| 출처 데이터셋 | uspto-grants-2014_05 |
| ORD ID | ord-c54a8973bc1b45e39e7e78dc6e8b723f |
| 출처 메모 | uspto-grants-2014_05 |