Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Isoxazolidine hydrochloride → 3-(4-Chloro-2-hydroxy-3-(isoxazolidin-2-ylsulfonyl)phenylamino)-4-ethoxycyclobut-3-ene-1,2-dione
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Isoxazolidine hydrochloride | HCID 12304500 | — |
| 반응물 | Ethyl(methoxy)amine hydrochloride | HCID 22613948 | — |
| 반응물 | 6-Chloro-3-(2-ethoxy-3,4-dioxo-cyclobut-1-enylamino)-2-hydroxy-N-methoxy-N-ethyl-benzenesulfonamide | HCID 86638631 | — |
| 생성물 | 3-(4-Chloro-2-hydroxy-3-(isoxazolidin-2-ylsulfonyl)phenylamino)-4-ethoxycyclobut-3-ene-1,2-dione | HCID 86658404 | — |
반응 단계
This compound was prepared analogously to 6-chloro-3-(2-ethoxy-3,4-dioxo-cyclobut-1-enylamino)-2-hydroxy-N-methoxy-N-ethyl-benzenesulfonamide (Intermediate FA) by replacing N-ethyl-O-methylhydroxylamine hydrochloride (Intermediate G) with isoxazolidine hydrochloride. [M+H]+ 402.9
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08722925B2 |
| 출처 데이터셋 | uspto-grants-2014_05 |
| ORD ID | ord-e0f6396d7865471bbd0552441adfe1f6 |
| 출처 메모 | uspto-grants-2014_05 |