L-Norvaline → (2S,3S)-3-Amino-N-cyclopropyl-2-hydroxyhexanamide

HRID 1025301노트

반응식

HRID 1025301 반응식
[NH2:1][C@@H:2]([CH2:11][CH3:12])[C@H:3]([OH:10])[C:4]([NH:6][CH:7]1[CH2:9][CH2:8]1)=[O:5].N[C@@H:14](CCC)C(O)=O>>[NH2:1][C@@H:2]([CH2:11][CH2:12][CH3:14])[C@H:3]([OH:10])[C:4]([NH:6][CH:7]1[CH2:8][CH2:9]1)=[O:5]

참가 물질

3

반응물 2

HCID 65098L-NorvalineHCID 57872123(2S,3S)-3-amino-N-cyclopropyl-2-hydroxypentanamide

생성물 1

HCID 16739337(2S,3S)-3-Amino-N-cyclopropyl-2-hydroxyhexanamide

실험 절차

The title compound was prepared in analogy to (2S,3S)-3-amino-N-cyclopropyl-2-hydroxypentanamide, Representative Procedure B, using (S)-2-aminopentanoic acid in the first step (step B1).

출처 및 근거

ORD 기록
ord-8b911e810af14ed6bc02981234417643
출처 데이터셋
uspto-grants-2014_05
특허 번호
US08729061B2

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