tert-butyl N-(1-hydroxy-2-methylpropan-2-yl)carbamate → 3-amino-N-cyclopropyl-2-hydroxy-3-methylbutanamide

HRID 1025302

반응식

HRID 1025302 반응식
Cl.Cl.[NH2:3][C@@H:4]([CH2:13]C)[C@H:5]([OH:12])[C:6]([NH:8][CH:9]1[CH2:11][CH2:10]1)=[O:7].O[CH2:16]C(NC(=O)OC(C)(C)C)(C)C>>[NH2:3][C:4]([CH3:13])([CH3:16])[CH:5]([OH:12])[C:6]([NH:8][CH:9]1[CH2:10][CH2:11]1)=[O:7]

참가 물질

3

반응물 2

HCID 14578673tert-butyl N-(1-hydroxy-2-methylpropan-2-yl)carbamateHCID 86762404(2S,3S)-3-amino-N-cyclopropyl-2-hydroxypentanamide dihydrochloride

생성물 1

HCID 575620933-amino-N-cyclopropyl-2-hydroxy-3-methylbutanamide

실험 절차

The title compound was prepared in analogy to (2S,3S)-3-amino-N-cyclopropyl-2-hydroxypentanamide dihydrochloride, Representative Procedure A, starting with tert-butyl 1-hydroxy-2-methylpropan-2-ylcarbamate in the second step (A2).

출처 및 근거

ORD 기록
ord-9b68c9b4801649729f8cf86cc2f551ea
출처 데이터셋
uspto-grants-2014_05
특허 번호
US08729061B2

연결된 노트

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