L-Valinol → (2S,3S)-3-Amino-N-cyclopropyl-2-hydroxy-4-methylpentanamide dihydrochloride

HRID 1025304

반응식

HRID 1025304 반응식
[ClH:1].Cl.[NH2:3][C@@H:4]([CH2:13][CH3:14])[C@H:5]([OH:12])[C:6]([NH:8][CH:9]1[CH2:11][CH2:10]1)=[O:7].N[C@@H:16](C(C)C)CO>>[ClH:1].[ClH:1].[NH2:3][C@@H:4]([CH:13]([CH3:16])[CH3:14])[C@H:5]([OH:12])[C:6]([NH:8][CH:9]1[CH2:10][CH2:11]1)=[O:7]

참가 물질

3

반응물 2

HCID 640993L-ValinolHCID 86762404(2S,3S)-3-amino-N-cyclopropyl-2-hydroxypentanamide dihydrochloride

생성물 1

HCID 86762405(2S,3S)-3-Amino-N-cyclopropyl-2-hydroxy-4-methylpentanamide dihydrochloride

실험 절차

The title compound was prepared in analogy to (2S,3S)-3-amino-N-cyclopropyl-2-hydroxypentanamide dihydrochloride, Representative Procedure A, starting with (S)-2-amino-3-methylbutan-1-ol in the first step (A1).

출처 및 근거

ORD 기록
ord-a2f243b3906b46ce9f20458b27178026
출처 데이터셋
uspto-grants-2014_05
특허 번호
US08729061B2

연결된 노트

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