L-Leucinol → (2S,3S)-3-Amino-N-cyclopropyl-2-hydroxy-5-methylhexanamide dihydrochloride

HRID 1025305

반응식

[ClH:1].Cl.N[C@@H](CC)[C@H](O)[C:6]([NH:8][CH:9]1[CH2:11][CH2:10]1)=[O:7].[NH2:15][C@@H:16]([CH2:19][CH:20]([CH3:22])[CH3:21])[CH2:17][OH:18]>>[ClH:1].[ClH:1].[NH2:15][C@@H:16]([CH2:19][CH:20]([CH3:22])[CH3:21])[C@H:17]([OH:18])[C:6]([NH:8][CH:9]1[CH2:11][CH2:10]1)=[O:7]

참가 물질

반응물 2

HCID 111307L-Leucinol

HCID 86762404(2S,3S)-3-amino-N-cyclopropyl-2-hydroxypentanamide dihydrochloride

생성물 1

HCID 86762407(2S,3S)-3-Amino-N-cyclopropyl-2-hydroxy-5-methylhexanamide dihydrochloride

실험 절차

The title compound was prepared in analogy to (2S,3S)-3-amino-N-cyclopropyl-2-hydroxypentanamide dihydrochloride, Representative Procedure A, starting with (S)-2-amino-4-methylpentan-1-ol in the first step (A1).

출처 및 근거

ORD 기록: ord-c760a3512d2640c28395d8c79a814798
출처 데이터셋: uspto-grants-2014_05
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08729061B2

연결된 노트

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