Ethane, isocyano- → (2S,3S)-3-Amino-N-ethyl-2-hydroxyhexanamide dihydrochloride

HRID 1025315

반응식

HRID 1025315 반응식
[ClH:1].Cl.[NH2:3][C@@H:4]([CH2:13][CH3:14])[C@H:5]([OH:12])[C:6]([NH:8][CH:9]1[CH2:11]C1)=[O:7].N[C@@H:16](CCC)CO.[N+](CC)#[C-]>>[ClH:1].[ClH:1].[NH2:3][C@@H:4]([CH2:13][CH2:14][CH3:16])[C@H:5]([OH:12])[C:6]([NH:8][CH2:9][CH3:11])=[O:7]

참가 물질

4

반응물 3

HCID 12226Ethane, isocyano-HCID 6951248(2S)-2-aminopentan-1-olHCID 86762404(2S,3S)-3-amino-N-cyclopropyl-2-hydroxypentanamide dihydrochloride

생성물 1

HCID 86762425(2S,3S)-3-Amino-N-ethyl-2-hydroxyhexanamide dihydrochloride

실험 절차

The title compound was prepared in analogy to (2S,3S)-3-amino-N-cyclopropyl-2-hydroxypentanamide dihydrochloride, Representative Procedure A, starting with (S)-2-aminopentan-1-ol in the first step (A1), and using isocyanoethane in the third step (A3).

출처 및 근거

ORD 기록
ord-f527261f78fb467ea44cf26c0c83afd2
출처 데이터셋
uspto-grants-2014_05
특허 번호
US08729061B2

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