Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
(3-(Trifluoromethyl)-1,2,4-oxadiazol-5-YL)methanamine → 5-bromo-6-(2,2,2-trifluoroethoxy)-N-((3-(trifluoromethyl)-1,2,4-oxadiazol-5-yl)methyl)nicotinamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | (3-(Trifluoromethyl)-1,2,4-oxadiazol-5-YL)methanamine | HCID 55263061 | — |
| 반응물 | 5-Bromo-6-(2,2,2-trifluoroethoxy)-3-pyridinecarboxylic acid | HCID 58192592 | — |
| 생성물 | 5-bromo-6-(2,2,2-trifluoroethoxy)-N-((3-(trifluoromethyl)-1,2,4-oxadiazol-5-yl)methyl)nicotinamide | HCID 86663143 | — |
반응 단계
The title compound was synthesized in analogy to Example 1 using 5-bromo-6-(2,2,2-trifluoroethoxy)-3-pyridinecarboxylic acid (CAN 1211586-75-2) and 3-trifluoromethyl-[1,2,4]oxadiazol-5-methanamine (example AK) as starting materials; LC-MS (UV peak area/ESI) 97%, 448.9532 (M−H)−.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08729105B2 |
| 출처 데이터셋 | uspto-grants-2014_05 |
| ORD ID | ord-0ea2edd16e1d4789ac75c8d60c20e58b |
| 출처 메모 | uspto-grants-2014_05 |