4-Phenylcyclohexanone → HCID 178418408, 화합물

반응식

[NH2:1][C:2]1[CH:7]=[CH:6][N:5]=[C:4]([CH:8]([CH3:10])[CH3:9])[C:3]=1[Cl:11].[C:12]1([CH:18]2[CH2:23][CH2:22][C:21](=O)[CH2:20][CH2:19]2)[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1>>[Cl:11][C:3]1[C:4]([CH:8]([CH3:9])[CH3:10])=[N:5][CH:6]=[CH:7][C:2]=1[NH:1][C@H:21]1[CH2:20][CH2:19][C@@H:18]([C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[CH2:23][CH2:22]1

참가 물질

반응물 2

HCID 786054-Phenylcyclohexanone

HCID 544250544-Amino-3-chloro-2-isopropylpyridine

생성물 1

HCID 178418408HCID 178418408, 화합물수율 26.6%

실험 절차

Was prepared analogously to Example 75 starting from 4-amino-3-chloro-2-isopropylpyridine and 4-phenylcyclohexanone. Yield: 26.6%

출처 및 근거

ORD 기록: ord-4950a24c3bb24e6eb853f7c03d0888b7
출처 데이터셋: uspto-grants-1998_03
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05723450

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