[3-(Trifluoromethyl)-1,2-oxazol-5-yl]methanamine → 4-(4-Chloro-phenyl)-5-cyclopropylmethoxy-pyrimidine-2-carboxylic acid (3-trifluoromethyl-isoxazol-5-ylmethyl)-amide
반응식
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[C:13]([O:14][CH2:15][CH:16]3[CH2:18][CH2:17]3)=[CH:12][N:11]=[C:10]([C:19]([OH:21])=O)[N:9]=2)=[CH:4][CH:3]=1.[F:22][C:23]([F:32])([F:31])[C:24]1[CH:28]=[C:27]([CH2:29][NH2:30])[O:26][N:25]=1>>[F:32][C:23]([F:22])([F:31])[C:24]1[CH:28]=[C:27]([CH2:29][NH:30][C:19]([C:10]2[N:9]=[C:8]([C:5]3[CH:4]=[CH:3][C:2]([Cl:1])=[CH:7][CH:6]=3)[C:13]([O:14][CH2:15][CH:16]3[CH2:17][CH2:18]3)=[CH:12][N:11]=2)=[O:21])[O:26][N:25]=1참가 물질
3
실험 절차
The title compound was synthesized in analogy to Example 1, using 4-(4-chloro-phenyl)-5-cyclopropylmethoxy-pyrimidine-2-carboxylic acid (example T) and 3-trifluoromethyl-isoxazol-5-methanamine (example BA) as starting materials; MS: 453.1 (M+H)+.
출처 및 근거
- ORD 기록
- ord-5905371e18d945e7a7e4ea3ed5d29ef1
- 출처 데이터셋