4-Aminobenzene-1,3-diol hydrochloride → 5-bromo-3-chloro-N-(2,4-dihydroxyphenyl)pyridine-2-carboxamide

반응식

[Br:1][C:2]1[CH:3]=[C:4]([Cl:11])[C:5]([C:8]([OH:10])=O)=[N:6][CH:7]=1.Cl.[NH2:13][C:14]1[CH:19]=[CH:18][C:17]([OH:20])=[CH:16][C:15]=1[OH:21]>>[Br:1][C:2]1[CH:3]=[C:4]([Cl:11])[C:5]([C:8]([NH:13][C:14]2[CH:19]=[CH:18][C:17]([OH:20])=[CH:16][C:15]=2[OH:21])=[O:10])=[N:6][CH:7]=1

참가 물질

반응물 2

HCID 134088224-Aminobenzene-1,3-diol hydrochloride

HCID 459338155-Bromo-3-chloropyridine-2-carboxylic acid

생성물 1

HCID 677778575-bromo-3-chloro-N-(2,4-dihydroxyphenyl)pyridine-2-carboxamide

실험 절차

Using 5-bromo-3-chloropyridine-2-carboxylic acid and 4-aminobenzene-1,3-diol hydrochloride, and in the same manner as in Example 2, step C, the title compound was obtained.

출처 및 근거

ORD 기록: ord-d49f1e60cc9e4d0eb98f6fda406aac52
출처 데이터셋: uspto-grants-2014_05
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08729102B2

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