2-[(1S)-2-Hydroxy-1-methylethyl]-1H-isoindole-1,3(2H)-dione → HCID 67778378, 화합물

반응식

[F:1][C:2]1[C:3]([OH:8])=[N:4][O:5][C:6]=1[CH3:7].O[CH2:10][C@@H:11]([N:13]1[C:21](=[O:22])[C:20]2[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=2)[C:14]1=[O:23])[CH3:12]>>[F:1][C:2]1[C:3]([O:8][CH2:12][C@@H:11]([N:13]2[C:21](=[O:22])[C:20]3[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=3)[C:14]2=[O:23])[CH3:10])=[N:4][O:5][C:6]=1[CH3:7]

참가 물질

반응물 2

HCID 124997532-[(1S)-2-Hydroxy-1-methylethyl]-1H-isoindole-1,3(2H)-dione

HCID 178435012HCID 178435012, 화합물

생성물 1

HCID 67778378HCID 67778378, 화합물

실험 절차

Using 4-fluoro-5-methylisoxazol-3-ol and 2-[(1S)-2-hydroxy-1-methylethyl]-1H-isoindole-1,3(2H)-dione, and in the same manner as in Example 1, step B, the title compound was obtained.

출처 및 근거

ORD 기록: ord-7a3e35a2994042f0982028a3485a49b3
출처 데이터셋: uspto-grants-2014_05
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08729102B2

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