HCID 178430719, 화합물 → HCID 178430713, 화합물
반응식
[CH3:1][C:2]1[CH:3]=[C:4]([N+:9]([O-])=O)[C:5]([OH:8])=[N:6][CH:7]=1>O1CCCC1.CO.[C].[Pd]>[NH2:9][C:4]1[C:5]([OH:8])=[N:6][CH:7]=[C:2]([CH3:1])[CH:3]=1참가 물질
5
실험 절차
At room temperature, to a mixed solvent solution of 5-methyl-3-nitropyridin-2-ol (5.0 g) in tetrahydrofuran (200 ml) and methanol (200 ml) was added 10% palladium carbon (0.5 g), followed by stirring for 24 hours under a hydrogen atmosphere. The reaction solution was filtered through Celite, and then the filtrate was concentrated under reduced pressure to afford 3-amino-5-methylpyridin-2-ol (4.03 g).
후처리
- filtrationThe reaction solution was filtered through Celite
- concentrationthe filtrate was concentrated under reduced pressure
출처 및 근거
- ORD 기록
- ord-578374b537694e4eb7bab951793381ef
- 출처 데이터셋
- uspto-grants-2014_05
- 특허 번호
- US08729095B2
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