Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Bromine → 6-Amino-5-bromopyridine-3-carbonitrile
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Bromine | HCID 24408 | — |
| 반응물 | 2-Amino-5-cyanopyridine | HCID 818260 | — |
| 용매 | Acetic Acid | HCID 176 | — |
| 생성물 | 6-Amino-5-bromopyridine-3-carbonitrile | HCID 1491250 | 49.5% |
반응 단계
Br2 (0.52 mL, 0.01 mol) was added to a solution of 6-aminonicotinonitrile (1.1901 g, 0.01 mol) in AcOH (10 mL) at room temperature. The mixture was stirred at room temperature for 2 h. Then the mixture was concentrated and the residue was purified by flash column chromatography to give the title product (980.0 mg, 49%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08735440B2 |
| 출처 데이터셋 | uspto-grants-2014_05 |
| ORD ID | ord-1f7dffa32c274d558d4b0459e33724d8 |
| 출처 메모 | uspto-grants-2014_05 |