Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acetanilide → 5-Fluoro-2-methyl-1-phenyl-1H-benzoimidazole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acetanilide | HCID 904 | — |
| 반응물 | 1-Bromo-4-fluoro-2-nitrobenzene | HCID 2773383 | — |
| 생성물 | 5-Fluoro-2-methyl-1-phenyl-1H-benzoimidazole | HCID 25216869 | 61% |
반응 단계
The title compound was prepared with the analogous procedure described in example 3 using 1-Bromo-4-fluoro-2-nitrobenzene and N-phenylacetamide (81 mg, 0.6 mmol) as starting materials to yield the title compound as brown solid (69 mg, 61%). 1H NMR (DMSO) δ 2.49 (s, 3 H), 7.17-7.32 (m, 2 H), 7.61-7.73 (m, 6 H).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08735586B2 |
| 출처 데이터셋 | uspto-grants-2014_05 |
| ORD ID | ord-2a3dc422c3d043f981b6dabd057aa724 |
| 출처 메모 | uspto-grants-2014_05 |