Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Bromine → Ethyl 3-bromo-2-oxobutanoate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Bromine | HCID 24408 | — |
| 반응물 | ethyl acetoacetate, sodium salt | HCID 85195 | — |
| 용매 | Chloroform | HCID 6212 | — |
| 생성물 | Ethyl 3-bromo-2-oxobutanoate | HCID 11117285 | — |
반응 단계
The 2-oxo-butyric acid ethyl ester prepared above was dissolved in chloroform (100 mL) and bromine (20.964 g, 131.19 mmol) was added dropwise at room temperature. The reaction mixture was allowed to stir for 18 h. Concentration of the reaction mixture under reduced pressure provided 12.0 g of the title compound as an orange oil. 1H NMR (CDCl3) δ 4.39 (q, 2H), 4.32 (q, 1H), 1.88 (d, 3H), 1.39 (t, 3H).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08735588B2 |
| 출처 데이터셋 | uspto-grants-2014_05 |
| ORD ID | ord-a3102cce8b0343389afa889c1c18dcc1 |
| 출처 메모 | uspto-grants-2014_05 |