Iodine → 2-Bromo-8-iododibenzofuran
반응식
[Br:1][C:2]1[CH:14]=[CH:13][C:5]2[O:6][C:7]3[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=3[C:4]=2[CH:3]=1.[I:15](O)(O)(O)(O)(O)=O.II.S(=O)(=O)(O)O>O.C(O)(=O)C>[Br:1][C:2]1[CH:14]=[CH:13][C:5]2[O:6][C:7]3[CH:12]=[CH:11][C:10]([I:15])=[CH:9][C:8]=3[C:4]=2[CH:3]=1참가 물질
7
반응 조건
- 온도
- 70 °C
실험 절차
2-Bromodibenzofuran (2.5 g, 10.1 mmol), orthoperiodic acid (0.49 g, 2.15 mmol), iodine (1.02 g, 4.02 mmol), sulfuric acid, H2O (2 ml) and acetic acid (10 ml) are put into a reaction vessel and the mixture is stirred at 70° C. for 3 hours. After cooling to room temperature the reaction mixture is poured into water and filtered. The white solid is washed by methanol and the desired product is obtained (1.92 g, 51%).
후처리
- temperatureAfter cooling to room temperature the reaction mixture
- filtrationfiltered
- washThe white solid is washed by methanol
출처 및 근거
- ORD 기록
- ord-1b9c8504b0da4d48ab06fb0f5714c765
- 출처 데이터셋
- uspto-grants-2014_05
- 특허 번호
- US08735610B2
반응 노트
불러오는 중…