참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Oxalyl chloride | HCID 65578 | — |
| 반응물 | 2-Bromo-3-methylbenzoic acid | HCID 2735588 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 2-Bromo-3-methylbenzoyl chloride | HCID 14174375 | — |
반응 단계
A suspension of 2-bromo-3-methylbenzoic acid (2.07 g, 9.63 mmol) in DCM (48.1 mL) was cooled to 0° C. Oxalyl chloride (0.9 mL, 10.14 mmol) was added dropwise via syringe. After addition, the cooling bath was removed and the reaction mixture stirred overnight. The mixture was concentrated in vacuo to remove solvent and excess reagent, affording 2-bromo-3-methylbenzoyl chloride as a cloudy white oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US08735384B2 |
|---|
| 출처 데이터셋 | uspto-grants-2014_05 |
|---|
| ORD ID | ord-83032d37c54a46f5b993f92c72bb64b3 |
|---|
| 출처 메모 | uspto-grants-2014_05 |
|---|
