Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
5,6,7,8-Tetrahydro-2-naphthylamine → 9-(5,6,7,8-Tetrahydro-naphthalen-2-ylamino)-5H-benzo[c][1,8]naphthyridin-6-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 5,6,7,8-Tetrahydro-2-naphthylamine | HCID 75193 | — |
| 반응물 | HCID 58168298 | HCID 58168298 | — |
| 생성물 | 9-(5,6,7,8-Tetrahydro-naphthalen-2-ylamino)-5H-benzo[c][1,8]naphthyridin-6-one | HCID 58168221 | 65.2% |
반응 단계
The title compound was synthesized according to the procedure described for the preparation of Example 231 using 6 (50 mg, 0.22 mmol) and 5,6,7,8-tetrahydro-2-naphthylamine (96 mg; 0.65 mmol) to provide 248 (49 mg, 27% yield) as a brown solid. LC-MS (M+H (parent)=343, obsd.=343).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08735584B2 |
| 출처 데이터셋 | uspto-grants-2014_05 |
| ORD ID | ord-4d044e3de9e44f469321f7a065894345 |
| 출처 메모 | uspto-grants-2014_05 |