Benzamide, N-(4-aminophenyl)- → N-(4-(9-Chloro-6-oxo-5,6-dihydrobenzo[c][1,8]naphthyridin-1-ylamino)phenyl)benzamide

HRID 1029236

반응식

HRID 1029236 반응식
Cl[C:2]1[CH:11]=[CH:10][N:9]=[C:8]2[C:3]=1[C:4]1[CH:16]=[C:15]([Cl:17])[CH:14]=[CH:13][C:5]=1[C:6](=[O:12])[NH:7]2.[NH2:18][C:19]1[CH:24]=[CH:23][C:22]([NH:25][C:26](=[O:33])[C:27]2[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=2)=[CH:21][CH:20]=1>>[Cl:17][C:15]1[CH:14]=[CH:13][C:5]2[C:6](=[O:12])[NH:7][C:8]3[C:3]([C:4]=2[CH:16]=1)=[C:2]([NH:18][C:19]1[CH:24]=[CH:23][C:22]([NH:25][C:26](=[O:33])[C:27]2[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=2)=[CH:21][CH:20]=1)[CH:11]=[CH:10][N:9]=3

참가 물질

3

반응물 2

HCID 87196Benzamide, N-(4-aminophenyl)-HCID 698092601,9-dichloro-5H-benzo[c][1,8]naphthyridin-6-one

생성물 1

HCID 44206162N-(4-(9-Chloro-6-oxo-5,6-dihydrobenzo[c][1,8]naphthyridin-1-ylamino)phenyl)benzamide

실험 절차

The title compound was synthesized according to the procedure described for the preparation of Example 267 using 1,9-dichloro-5H-benzo[c][1,8]naphthyridin-6-one and N-(4-aminophenyl)benzamide to provide 293. LC-MS (M+H=442, obsd.=442).

후처리

  1. customThe title compound was synthesized

출처 및 근거

ORD 기록
ord-02aa50ea7deb4ece9bd306916c7a73d4
출처 데이터셋
uspto-grants-2014_05
특허 번호
US08735584B2

연결된 노트

불러오는 중…