Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Triethylamine → 5-Chloro-2-(methylthio)benzothiazole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | 1H-Pyrazol-5-ol, 3-methyl-1-phenyl- | HCID 70335 | — |
| 반응물 | 3-[5-Chloro-2-(methylthio)-1,3-benzothiazol-3-ium-3-yl]-1-propanesulfonate | HCID 4383736 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | 5-Chloro-2-(methylthio)benzothiazole | HCID 645746 | — |
반응 단계
3-Methyl-1-phenylpyrazolin-5-one (1.045 g) was mixed with 2.03 g (0.006 mol) 2-methylthio-5-chloro-3-(3'-sulfopropyl)benzothiazolium, inner salt in 50 ml methanol. Triethylamine (0.62 g) was added. The mixture was stirred for one hour, the solvent evaporated, and the residue dissolved in isopropanol. The resulting solution was treated with 0.6 g KOAc in methanol to precipitate the dye. Filtering yielded 2.17 g (72%), mp 271°-276° C., λmax=383 (ε=19,000).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05102781 |
| 출처 데이터셋 | uspto-grants-1992_04 |
| ORD ID | ord-3c95269e58ae498b8021c76427471d47 |
| 출처 메모 | uspto-grants-1992_04 |