Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Triethylamine → 4-[-3-Methylbenzothiazolinylidene]-3-methyl-1-phenylpyrazolin-5-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | Benzothiazolium, 3-methyl-2-(methylthio)-, 4-methylbenzenesulfonate (1:1) | HCID 41464 | — |
| 반응물 | 1H-Pyrazol-5-ol, 3-methyl-1-phenyl- | HCID 70335 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | 4-[-3-Methylbenzothiazolinylidene]-3-methyl-1-phenylpyrazolin-5-one | HCID 86745611 | — |
반응 단계
3-Methyl-1-phenylpyrazolin-5-one (1.74 g, 0.01 mol) was mixed with 3.68 g (0.01 mol) 2-methylthio-3-methylbenzothiazolium tosylate in 25 ml methanol. Triethylamine (1.01 g, 0.01 mol) was added. The mixture was stirred for one hour, then filtered and washed with methanol. After drying the yield was 2.46 g (78%), mp 159°-162° C., λmax=375 (ε=25,000).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05102781 |
| 출처 데이터셋 | uspto-grants-1992_04 |
| ORD ID | ord-6cbb14defca149e0998b6ab85d6dad14 |
| 출처 메모 | uspto-grants-1992_04 |