Triethylamine → 4-[5-Methoxy-3-methylbenzothiazolinylidene]-3-methyl-1-phenylpyrazolin-5-on

HRID 1029358

반응식

HRID 1029358 반응식
[CH3:1][C:2]1[NH:3][N:4]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[C:5](=[O:7])[CH:6]=1.S(C1C=CC(C)=CC=1)([O-])(=O)=O.[CH3:25][O:26][C:27]1[CH:28]=[CH:29][C:30]2[S:34][C:33](SC)=[N+:32]([CH3:37])[C:31]=2[CH:38]=1.C(N(CC)CC)C>CO>[CH3:25][O:26][C:27]1[CH:28]=[CH:29][C:30]2[S:34](=[C:6]3[C:5](=[O:7])[N:4]([C:8]4[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=4)[NH:3][CH:2]3[CH3:1])[CH2:33][N:32]([CH3:37])[C:31]=2[CH:38]=1

참가 물질

5

반응물 3

HCID 8471TriethylamineHCID 703351H-Pyrazol-5-ol, 3-methyl-1-phenyl-HCID 867456125-Methoxy-2-methylthio-3-methylbenzothiazolium tosylate

생성물 1

HCID 867456134-[5-Methoxy-3-methylbenzothiazolinylidene]-3-methyl-1-phenylpyrazolin-5-on

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

3-Methyl-1-phenylpyrazolin-5-one (1.74 g, 0.01 mol) was mixed with 3.97 g (0.01 mol) 5-methoxy-2-methylthio-3-methylbenzothiazolium tosylate in 25 ml methanol. Triethylamine (1.01 g, 0.01 mol) was added. The mixture was stirred for 3.5 hours, then filtered and washed with methanol. After drying the yield was 276 g (79%), mp 155°-156° C., λmax=386 (ε=25,000).

후처리

  1. filtrationfiltered
  2. washwashed with methanol
  3. customAfter drying the yield was 276 g (79%), mp 155°-156° C., λmax=386 (ε=25,000)

출처 및 근거

ORD 기록
ord-5ddf10501a9142da9f7d5ad3f0804a4a
출처 데이터셋
uspto-grants-1992_04
특허 번호
US05102781

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