4-(4-Chlorophenyl)butan-1-ol → 4-(4-Chlorophenyl)butanal
반응식
[Cr](Cl)([O-])(=O)=O.[NH+]1C=CC=CC=1.[Cl:12][C:13]1[CH:18]=[CH:17][C:16]([CH2:19][CH2:20][CH2:21][CH2:22][OH:23])=[CH:15][CH:14]=1>C(Cl)Cl>[Cl:12][C:13]1[CH:14]=[CH:15][C:16]([CH2:19][CH2:20][CH2:21][CH:22]=[O:23])=[CH:17][CH:18]=1참가 물질
4
실험 절차
To a suspension of pyridinium chlorochromate (PCC) (5 g) in CH2Cl2 (200 mL) and 4 angstrom molecule sieves (5 g) was added the alcohol (2 g) (Step II). The mixture was stirred 2 hr at RT, filtered through celite and evaporated. Flash chromatography using 25% ethyl acetate in hexane afforded the title compound.
후처리
- filtrationfiltered through celite
- customevaporated
출처 및 근거
- ORD 기록
- ord-2ed6c4e2e3e44577aed5c014581df04d
- 출처 데이터셋
- uspto-grants-1992_04
- 특허 번호
- US05102881
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