2-Benzothiazolinone, hydrazone → HCID 14851333, 화합물

HRID 1029467

반응식

HRID 1029467 반응식
[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8](=O)[CH2:9][C:10](=O)[CH:11]([CH3:13])[CH3:12])=[CH:4][CH:3]=1.[NH:16]([C:18]1[S:19][C:20]2[CH:26]=[CH:25][CH:24]=[CH:23][C:21]=2[N:22]=1)[NH2:17]>C(O)(=O)C>[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[N:16]([C:18]3[S:19][C:20]4[CH:26]=[CH:25][CH:24]=[CH:23][C:21]=4[N:22]=3)[N:17]=[C:10]([CH:11]([CH3:13])[CH3:12])[CH:9]=2)=[CH:4][CH:3]=1

참가 물질

4

반응물 2

HCID 119882-Benzothiazolinone, hydrazoneHCID 141543761-(4-Fluorophenyl)-4-methylpentane-1,3-dione

생성물 1

HCID 14851333HCID 14851333, 화합물수율 92.2%

시약·촉매·용매 1

HCID 176Acetic Acid용매

실험 절차

To a solution of the 1,3-diketone (103 g, 495 mmol) (preparation described in Example 1, Step A) in glacial acetic acid (800 mL) was added 2-hydrazinobenzothiazole (85.8 g, 520 mmol). The resulting solution was refluxed for 2.5 hours and then cooled to room temperature overnight. The resulting precipitate was collected, washed with water and dried overnight to give 154 g (92%) of a cream colored solid.

후처리

  1. temperatureThe resulting solution was refluxed for 2.5 hours
  2. customThe resulting precipitate was collected
  3. washwashed with water
  4. customdried overnight

출처 및 근거

ORD 기록
ord-9fa8270522b34bd08b28b52938339b09
출처 데이터셋
uspto-grants-1992_04
특허 번호
US05102893

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