1-(Benzyloxy)-2,3-dinitrobenzene → 3-(Benzyloxy)benzene-1,2-diamine

HRID 1030520노트

반응식

HRID 1030520 반응식
[CH2:1]([O:8][C:9]1[C:10]([N+:18]([O-])=O)=[C:11]([N+:15]([O-])=O)[CH:12]=[CH:13][CH:14]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[H][H]>C(O)C.[Ni]>[CH2:1]([O:8][C:9]1[C:10]([NH2:18])=[C:11]([NH2:15])[CH:12]=[CH:13][CH:14]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

참가 물질

4

반응물 2

HCID 139713581-(Benzyloxy)-2,3-dinitrobenzeneHCID 178418361HCID 178418361, 화합물

생성물 1

HCID 44012883-(Benzyloxy)benzene-1,2-diamine수율 102.3%

시약·촉매·용매 1

HCID 86745698ethanol Raney-nickel용매

실험 절차

To a solution of 3-benzyloxy-1,2-dinitrobenzene (2 g, 0.0073 mol) in 300 ml ethanol Raney-nickel (1 g) was added and the mixture was hydrogenated at room temperature and atmospheric pressure until the uptake of hydrogen ceased (30 min). The colourless solution was filtered (celite) and evaporated to dryness in vacuo to give the title compound as an unstable oil (1.6 g) which was used immediately for the next step.

후처리

  1. customwas hydrogenated at room temperature
  2. custom(30 min)
  3. filtrationThe colourless solution was filtered (celite)
  4. customevaporated to dryness in vacuo

출처 및 근거

ORD 기록
ord-c18ccd15a23a4d11834ee6c982afc680
출처 데이터셋
uspto-grants-1992_04
특허 번호
US05106862

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