참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | 2-(Bromomethyl)-4-fluoro-1-nitrobenzene | HCID 10561643 | — |
| 반응물 | Phthalimide potassium salt | HCID 24194345 | — |
| 용매 | Water | HCID 962 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | N-(5-fluoro-2-nitrophenyl)methyl-phthalimide | HCID 19820552 | — |
반응 단계
A solution of 5-fluoro-2-nitro-benzylbromide (6.2 g) in dimethylformamide (20 ml) was dropped into a stirred suspension of potassium phthalimide (4.9 g) in the same solvent (40 ml). The mixture was heated under stirring to 90° C. for 2 hours, then cooled and diluted with water. The title compound (7.2 g) was recovered by filtration. M.p. 198°-200° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US05106851 |
|---|
| 출처 데이터셋 | uspto-grants-1992_04 |
|---|
| ORD ID | ord-bab01ec25e174a5e9e8ea8ea18f37e6f |
|---|
| 출처 메모 | uspto-grants-1992_04 |
|---|
