HCID 14078470, 화합물 → 4-Methoxybenzaldehyde

HRID 1030735노트

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HRID 1030735 반응식
O[C:2]1[C:7](CC=C(C)C)=[C:6]([O:13][CH3:14])[CH:5]=[CH:4][C:3]=1[C:15](=[O:17])C>C(O)C>[CH:15](=[O:17])[C:3]1[CH:2]=[CH:7][C:6]([O:13][CH3:14])=[CH:5][CH:4]=1

참가 물질

3

반응물 1

HCID 14078470HCID 14078470, 화합물

생성물 1

HCID 312444-Methoxybenzaldehyde

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

In 5 ml of ethanol were dissolved 0.48 g of 2'-hydroxy-4'-methoxy-3'-(3-methyl-2-butenyl)acetophenone obtained in production Example 9 and 0.35 ml of p-anisaldehyde. The solution was cooled to 0° C. and 7.5 ml of a saturated ethanol solution of potassium hydroxide was added to the solution, and the mixture was stirred at 0° C for 30 minutes and at room temperature for 4 days. After the reaction, 3N hydrochloric acid was added to the reaction liquid under cooling to gradually make the liquid acidic, and the formed precipitate was recovered by filtration and recrystallized from methanol to obtain 0.47 g (yield=64.7%) of 2'-hydroxy-4,4'-dimethoxy-3'-(3-methyl-2-butenyl)chalcone in the form of a yellow needle.

출처 및 근거

ORD 기록
ord-49ce5b3fc9b541c1a0cbdb372179414d
출처 데이터셋
uspto-grants-1992_04
특허 번호
US05106871

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