참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Benzenemethanol, 2-[(2-methylpropyl)amino]- | HCID 10130218 | — |
| 생성물 | 2-(Isobutylamino)benzyl chloride hydrochloride | HCID 14839436 | 68% |
반응 단계
In 190 ml of conc. hydrochloric acid was dissolved 19.1 g of 2-(isobutylamino)benzyl alcohol, and the solution was heated in a sealed tube at 100° C. for 40 min. The reaction mixture was stirred for 30 min. under chilling with ice and the precipitated crystals were collected by filtration. The collected crystals were washed successively with hydrochloric acid and acetone and dried to give 16.9 g (yield: 68%) of 2-(isobutylamino)benzyl chloride hydrochloride as a white crystalline product.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US05106976 |
|---|
| 출처 데이터셋 | uspto-grants-1992_04 |
|---|
| ORD ID | ord-d7d07fa9f7ad4a61a7f7e61ebfa84079 |
|---|
| 출처 메모 | uspto-grants-1992_04 |
|---|
